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https://hdl.handle.net/20.500.14094/90006123
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2024-04-24
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90006123 (fulltext)
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メタデータID
90006123
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open access
出版タイプ
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タイトル
Feeding interval and use of donor breast milk for very low birthweight infants: A nationwide survey in Japan
著者
Ashina, Mariko ; Fujioka, Kazumichi ; Totsu, Satsuki ; Shoji, Hiromichi ; Miyazawa, Tokuo ; Wada, Kazuko ; Iijima, Kazumoto ; Morioka, Ichiro
著者名
Ashina, Mariko
著者ID
A0863
研究者ID
1000020568810
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=61a996a431fe1218520e17560c007669
著者名
Fujioka, Kazumichi
藤岡, 一路
フジオカ, カズミチ
所属機関名
医学部附属病院
著者名
Totsu, Satsuki
著者名
Shoji, Hiromichi
著者名
Miyazawa, Tokuo
著者名
Wada, Kazuko
著者ID
A0877
研究者ID
1000000240854
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=1a50a9148347284a520e17560c007669
著者名
Iijima, Kazumoto
飯島, 一誠
イイジマ, カヅモト
所属機関名
医学研究科
著者ID
A1383
研究者ID
1000080437467
著者名
Morioka, Ichiro
森岡, 一朗
モリオカ, イチロウ
所属機関名
医学研究科
収録物名
Pediatrics & Neonatology
巻(号)
60(3)
ページ
245-251
出版者
Elsevier Taiwan
刊行日
2019-06
公開日
2019-06-25
抄録
Background: Enteral feeding is critical for postnatal growth of very low birthweight infants (VLBWI); however, a standard feeding strategy has not been established in Japan. A 2- or 3-h feeding interval is generally used, but no clear evidence supports either approach. Additionally, there is no nationwide breast milk bank in Japan and no consensus exists on the use of donor breast milk (DBM). To clarify the current feeding strategies for VLBWI in Japan, we undertook a nationwide survey. Methods: We sent a questionnaire to the 382 NICUs included in the Neonatal Research Network in Japan. We sought information on NICU size, number of admissions, necrotizing enterocolitis (NEC) incidence, feeding interval, and use of DBM. Results: We received responses from 217 NICUs (56.8%), including 76 tertiary centers and 140 regional centers. We only analyzed data obtained from tertiary perinatal centers with a high response rate (77.6%) owing to the insufficient response rate of lower-level facilities (< 50%). Most NICUs (71.1%) used a 3-h feeding interval. Only 9.2% used a 2-h interval for all VLBWI. Most NICUs (64.5%) never used DBM, which is not routinely pasteurized. DBM was used in 27 NICUs (35.5%), with and without limitations. Data from 14,233 VLBWI were analyzed; 258 infants (1.8%) were diagnosed with NEC from 2011 to 2015. The incidence of NEC was higher in NICUs that used a 2-h interval (2.7%) than in others. No association was found between NEC and the use of DBM. The NEC incidence did not differ between centers using the most common strategy of a 3-h interval without DBM and those using other strategies. Conclusion: Most NICUs in Japan use a 3-h feeding interval and do not use DBM for VLBWI. Further prospective studies including multiple confounders are required to clarify the relationship between feeding strategy and the incidence of NEC.
キーワード
donor breast milk
enteral feeding
feeding interval
nationwide survey
very low birth weight infants
カテゴリ
医学研究科
医学部附属病院
学術雑誌論文
権利
© 2018 Taiwan Pediatric Association. Published by Elsevier Taiwan LLC.
This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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資源タイプ
journal article
言語
English (英語)
ISSN
1875-9572
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eISSN
2212-1692
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関連情報
DOI
https://doi.org/10.1016/j.pedneo.2018.07.006
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