神戸大学附属図書館デジタルアーカイブ
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https://hdl.handle.net/20.500.14094/90007404
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2024-04-26
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90007404 (fulltext)
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メタデータID
90007404
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open access
出版タイプ
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タイトル
Diagnostic performance of zero-TE lung MR imaging in FDG PET/MRI for pulmonary malignancies
著者
Zeng, Feibi ; Nogami, Munenobu ; Ueno, Yoshiko R. ; Kanda, Tomonori ; Sofue, Keitaro ; Kubo, Kazuhiro ; Kurimoto, Takako ; Murakami, Takamichi
著者名
Zeng, Feibi
著者ID
A2176
研究者ID
1000030464267
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=49edb5676835af3f520e17560c007669
著者名
Nogami, Munenobu
野上, 宗伸
ノガミ, ムネノブ
所属機関名
医学部附属病院
著者ID
A1480
研究者ID
1000050625134
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=516af1c99142505f520e17560c007669
著者名
Ueno, Yoshiko R.
上野, 嘉子
ウエノ, ヨシコ
所属機関名
医学研究科
著者ID
A2134
研究者ID
1000030514781
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=9e54f671f6262928520e17560c007669
著者名
Kanda, Tomonori
神田, 知紀
カンダ, トモノリ
所属機関名
医学研究科
著者ID
A1469
研究者ID
1000090622027
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=f7fcd4a60d373990520e17560c007669
著者名
Sofue, Keitaro
祖父江, 慶太郎
ソフエ, ケイタロウ
所属機関名
医学部附属病院
著者名
Kubo, Kazuhiro
著者名
Kurimoto, Takako
著者ID
A2302
研究者ID
1000020252653
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=4d5c2d2510f6d3a2520e17560c007669
著者名
Murakami, Takamichi
村上, 卓道
ムラカミ, タカミチ
所属機関名
医学研究科
収録物名
European Radiology
巻(号)
30(9)
ページ
4995-5003
出版者
Springer
刊行日
2020-09
公開日
2020-09-01
抄録
Objectives This study aimed to evaluate the diagnostic performance of the lung zero-echo time (ZTE) sequence in FDG PET/MRI for detection and differentiation of lung lesions in oncologic patients in comparison with conventional two-point Dixon-based MR imaging. Methods In this single-institution retrospective study approved by the institutional review board, 209 patients with malignancies (97 men and 112 women; age range, 17-89 years; mean age, 66.5 ± 12.9 years) underwent(18)F-FDG PET/MRI between August 2017 and August 2018, with diagnostic Dixon and ZTE under respiratory gating acquired simultaneously with PET. Image analysis was performed for PET/Dixon and PET/ZTE fused images by two readers to assess the detectability and differentiation of lung lesions. The reference standard was pathological findings and/or the data from a chest CT. The detection and differentiation abilities were evaluated for all lesions and subgroups divided by lesion size and maximum standardized uptake value (SUVmax). Results Based on the reference standard, 227 lung lesions were identified in 113 patients. The detectability of PET/ZTE was significantly better than that of PET/Dixon for overall lesions, lesions with a SUVmax less than 3.0 and lesions smaller than 4 mm (p < 0.01). The diagnostic performance of PET/ZTE was significantly better than that of PET/Dixon for overall lesions and lesions smaller than 4 mm (p < 0.01). Conclusions ZTE can improve diagnostic performance in the detection and differentiation of both FDG-avid and non-FDG-avid lung lesions smaller than 4 mm in size, yielding a promising tool to enhance the utility of FDG PET/MRI in oncology patients with lung lesions.
キーワード
Lung
Fluorodeoxyglucose F18
Magnetic resonance imaging
Positron-emission tomography
カテゴリ
医学研究科
医学部附属病院
学術雑誌論文
権利
© The Author(s) 2020.
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
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資源タイプ
journal article
言語
English (英語)
ISSN
0938-7994
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eISSN
1432-1084
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NCID
AA10824302
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関連情報
DOI
https://doi.org/10.1007/s00330-020-06848-z
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