神戸大学附属図書館デジタルアーカイブ
https://hdl.handle.net/20.500.14094/90007783

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メタデータID
90007783
アクセス権
open access
出版タイプ
Accepted Manuscript
タイトル
Effects of preoperative dental examination and oral hygiene instruction on surgical site infection after hepatectomy: a retrospective study
著者
Hasegawa, Takumi ; Takeda, Daisuke ; Tanaka, Motofumi ; Amano, Rika ; Saito, Izumi ; Kakei, Yasumasa ; Kimoto, Akira ; Fukumoto, Takumi ; Akashi, Masaya
著者ID
A1489
研究者ID
1000050546497
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=322ffbb7f3848e30520e17560c007669
著者名
Hasegawa, Takumi
長谷川, 巧実
ハセガワ, タクミ
所属機関名
医学研究科
著者ID
A2567
研究者ID
1000080755637
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=f59f62b200a1f47c520e17560c007669
著者名
Takeda, Daisuke
武田, 大介
タケダ, ダイスケ
所属機関名
医学部附属病院
著者ID
A1481
研究者ID
1000080435560
著者名
Tanaka, Motofumi
田中, 基文
タナカ, モトフミ
所属機関名
医学研究科
著者名
Amano, Rika
著者名
Saito, Izumi
著者ID
A2217
研究者ID
1000070772896
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=3e2a39a5f4448ccc520e17560c007669
著者名
Kakei, Yasumasa
筧, 康正
カケイ, ヤスマサ
所属機関名
医学部附属病院
著者ID
A2386
研究者ID
1000030597167
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=c598b50157255250520e17560c007669
著者名
Kimoto, Akira
木本, 明
キモト, アキラ
所属機関名
医学部附属病院
著者ID
A0787
研究者ID
1000070379402
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=cc75a09ef927fb18520e17560c007669
著者名
Fukumoto, Takumi
福本, 巧
フクモト, タクミ
所属機関名
医学研究科
著者ID
A1492
研究者ID
1000040597168
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/search/detail?systemId=b7649a2950dc725a520e17560c007669
著者名
Akashi, Masaya
明石, 昌也
アカシ, マサヤ
所属機関名
医学研究科
収録物名
Supportive Care in Cancer
巻(号)
29(2)
ページ
653-659
出版者
Springer
刊行日
2021-02
公開日
2022-03-01
抄録
Purpose This study retrospectively investigated relationships among risk factors and post-hepatectomy surgical site infection (SSI) and other complications in patients who underwent hepatectomy for hepatocellular carcinoma (HCC). Methods We included 334 patients who underwent hepatectomies for liver cancers between January 2011 and December 2015 in this study. We evaluated risk factors for SSI and other post-hepatectomy complication, including demographic factors, preoperative factors, and preoperative intervention including oral management, perioperative factors, and length of hospital stay, with univariate and multivariate analyses. The oral management intervention included self-care instructions, extraction of infected teeth, removal of dental plaques and calculus (scaling), professional mechanical teeth cleaning, removal of tongue coating, and cleaning of dentures. SSI was defined in accordance with the guideline issued by the Centers for Disease Control and Prevention; it included purulent discharge from any incision or organ space within 30 days postoperatively, with or without microbiological evidence. Complications of grade II or greater, according to the Clavien-Dindo classification, were regarded as postoperative complications. Results We found bacterial infection of ascites (Odds ratio (OR) = 13.72), lack of preoperative oral management intervention (OR = 10.17), and severe liver fibrosis (OR = 2.76) to be associated with SSI and severe liver fibrosis (OR = 2.28), hypoalbuminemia (OR = 2.02), blood transfusion (OR = 1.86), and longer operation time (OR = 1.80) to be associated with postoperative complications. Conclusions Preoperative oral management may reduce the risk of SSI in patients with HCC who undergo hepatectomy.
キーワード
Oral health care
Oral management
Hepatectomy
Infection
Complication
カテゴリ
医学研究科
医学部附属病院
学術雑誌論文
権利
© Springer-Verlag GmbH Germany, part of Springer Nature 2020. This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature's AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00520-020-05525-7