神戸大学附属図書館デジタルアーカイブ
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https://hdl.handle.net/20.500.14094/90007852
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2024-03-29
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90007852 (fulltext)
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メタデータID
90007852
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open access
出版タイプ
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タイトル
Effect of educational intervention on the appropriate use of oral antimicrobials in oral and maxillofacial surgery: a retrospective secondary data analysis
著者
Kusumoto, Junya ; Uda, Atsushi ; Kimura, Takeshi ; Furudoi, Shungo ; Yoshii, Ryosuke ; Matsumura, Megumi ; Miyara, Takayuki ; Akashi, Masaya
著者ID
A2832
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/profile/ja.594ee1f31af889e2520e17560c007669.html
著者名
Kusumoto, Junya
楠元, 順哉
クスモト, ジュンヤ
所属機関名
医学部附属病院
著者名
Uda, Atsushi
著者名
Kimura, Takeshi
著者ID
A1374
研究者ID
1000000397803
著者名
Furudoi, Shungo
古土井, 春吾
フルドイ, シュンゴ
所属機関名
医学部附属病院 手術部
著者名
Yoshii, Ryosuke
著者名
Matsumura, Megumi
著者ID
A2427
研究者ID
1000050368304
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/profile/ja.138f2af1dd8a86c0520e17560c007669.html
著者名
Miyara, Takayuki
宮良, 高維
ミヤラ, タカユキ
所属機関名
医学部附属病院
著者ID
A1492
研究者ID
1000040597168
KUID
https://kuid-rm-web.ofc.kobe-u.ac.jp/profile/ja.b7649a2950dc725a520e17560c007669.html
著者名
Akashi, Masaya
明石, 昌也
アカシ, マサヤ
所属機関名
医学研究科
収録物名
BMC Oral Health
巻(号)
21(1)
ページ
20-20
出版者
BMC
刊行日
2021-01-07
公開日
2021-02-12
抄録
Background In Japan, oral third-generation cephalosporins with broad-spectrum activity are commonly prescribed in the practices of dentistry and oral surgery. However, there are few reports on the appropriate use of antibiotics in the field of oral surgery. This study aimed to evaluate the appropriateness of antibiotic use before and after an educational intervention in the Department of Oral and Maxillofacial Surgery, Kobe University Hospital. Methods The use of oral antibiotics was investigated among inpatients and outpatients before and after an educational intervention conducted by the antimicrobial stewardship team. Additionally, the frequency of surgical site infection after the surgical removal of an impacted third mandibular molar under general anesthesia and the prevalence of adverse effects of the prescribed antibiotics were comparatively evaluated between 2013 and 2018. Results After the educational intervention, a remarkable reduction was noted in the prescription of oral third-generation cephalosporins, but increased use of penicillins was noted among outpatients. There was reduced use of macrolides and quinolones in outpatients. Although a similar trend was seen for inpatients, the use of quinolones increased in this population. Despite the change in the pattern of antibiotic prescription, inpatients who underwent mandibular third molar extraction between 2013 and 2018 did not show a significant increase in the prevalence of surgical site infections (6.2% vs. 1.8%, p=.336) and adverse effects of drugs (2.1% vs. 0%, p=.466). Conclusions This study suggests that the judicious use of oral antibiotics is possible through conscious and habitual practice of appropriate antibiotic use. However, further investigation is required to develop measures for appropriate use of oral antibiotics.
キーワード
Anti-bacterial agents
Antimicrobial resistance
Oral third-generation cephalosporin
Macrolide
Quinolone
Japan
Antibiotic stewardship
Oral-maxillofacial surgeon
Surgical site infection
カテゴリ
医学研究科
医学部附属病院
学術雑誌論文
権利
© The Author(s) 2021.
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
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資源タイプ
journal article
言語
English (英語)
eISSN
1472-6831
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NCID
AA11839983
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関連情報
DOI
https://doi.org/10.1186/s12903-020-01367-1
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