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Investigation of the potential of using TiO2 nanoparticles as a contrast agent in computed tomography and magnetic resonance imaging

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本文URL	ダウンロード回数：回
ID	90007446
資源タイプ	Journal Article / 学術雑誌論文
版区分	author
タイトル	Investigation of the potential of using TiO2 nanoparticles as a contrast agent in computed tomography and magnetic resonance imaging
著者ID	A1164 / A2247 / / / A2249 / / / / / / / / A1345 / A0339 / A1363
著者	Akasaka, Hiroaki Mukumoto, Naritoshi Nakayama, Masao Wang, Tianyuan Yada, Ryuichi Shimizu, Yasuyuki Inubushi, Sachiko Kyotani, Katsusuke Okumura, Keisuke Miyamoto, Masanori Nakaoka, Ai Morita, Kenta Nishimura, Yuya Ogino, Chiaki Sasaki, Ryohei
著者別表記	赤坂, 浩亮 / 椋本, 成俊 / / / 矢田, 隆一 / / / / / / / / 西村, 勇哉 / 荻野, 千秋 / 佐々木, 良平
著者ヨミ	アカサカ, ヒロアキムクモト, ナリトシヤダ, リュウイチニシムラ, ユウヤオギノ, チアキササキ, リョウヘイ
著者所属	医学部附属病院医学部附属病院医学部附属病院科学技術イノベーション研究科工学研究科医学部附属病院
掲載誌	Applied Nanoscience
巻号	10(8)
ページ	3143-3148
公開者	Springer Verlag
刊行日	2020-08
権利	© King Abdulaziz City for Science and Technology 2019. This is a post-peer-review, pre-copyedit version of an article published in Applied Nanoscience. The final authenticated version is available online at: https://doi.org/10.1007/s13204-019-01098-y
公開日	2021-09-01
ISSN	21905509
eISSN	21905517
DOI	10.1007/s13204-019-01098-y
言語	eng
研究者ID	1000020707161 / 1000070634278 / / / 1000050782421 / / / / / / / / 1000040728218 / 1000000313693 / 1000030346267
内容記述	Nanoparticles (NPs) are useful for radiotherapy. Currently, efforts are underway globally for the development of novel titanium dioxide NPs (TiO2-NPs) that exhibit both contrast effects and anti-tumor effects. In this study, the image contrast properties of TiO2-NPs were evaluated using a clinical magnetic resonance imaging (MRI) system and a clinical computed tomography (CT) scanner, as the use of TiO2-NPs as an anti-cancer agent has been reported in several reports. An obvious difference in visualization was observed between the control and TiO2-NP samples on T2-weighted images. These results suggest that TiO2 can potentially be used as a novel theranostic drug with radiosensitizing ability and radiological diagnostic ability, through modification of chemical groups on its surface, and as a component of drug delivery systems.
キーワード	Nanoparticle / Titanium oxide / Theranostic / MRI / CT / Radiotherapy
KUID	/ https://kuid-rm-web.ofc.kobe-u.ac.jp/profile/ja.79fcee28d118d94d520e17560c007669.html / / / https://kuid-rm-web.ofc.kobe-u.ac.jp/profile/ja.c8d8c66aeab29c3d520e17560c007669.html / / / / / / / / / https://kuid-rm-web.ofc.kobe-u.ac.jp/profile/ja.cb7c84b4e252c367520e17560c007669.html / https://kuid-rm-web.ofc.kobe-u.ac.jp/profile/ja.f5e9afd9968a7ac8520e17560c007669.html
データ登録日	2020-09-16

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